Murphy got his left foot caught under the screen. He pulled himself free and tried to walk off the mound but fell to the ground, where he remained for a few minutes while teammates and coaches gathered around him.
Preliminary reports indicated Murphy suffered a pulled left hamstring and injured knee. He was in obvious pain as he was helped off the field and taken directly into the clubhouse.
Astros officials said the injuries weren't serious.
Sandbags were placed on the screen following the incident as 17 mile per hour winds swept through O.Co Coliseum.
Rick Eymer is a contributor to MLB.com. This story was not subject to the approval of Major League Baseball or its clubs.