Manager Brad Mills said the toe has been bothering Cordero since July 25. Mills said the closer has been getting treatment, but the injury hasn't improved. He's optimistic a trip to the DL will allow Cordero to get completely healthy.
"It just really hasn't gotten that much better," Mills said. "We thought we wanted to get that well, get him feeling good. Hopefully along the way he'll start throwing the ball like we know he can."
Cordero has struggled since being a part of the 10-player trade the Astros and Blue Jays made July 20. He has given up 11 runs on 13 hits in five innings over six games for Houston.
With Cordero hurt, Mills said the Astros will use right-hander Wilton Lopez as their closer. Lopez is 3-0 with a 2.52 ERA in 39 1/3 innings this season. His 1.14 rate of walks per nine innings is the lowest among Major League relievers.
"He's done such a good job for us all year," Mills said. "He's the guy we want when we want to wrap it up."